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Systems

IJM NanoScaler GMP
designed for
METHOD DEVELOPMENT AND SCALE-UP
✔ Scale-up with 5 IJMs
✔ Encapsulation at a range of
✔ 500 µL to hundreds of milliliters
✔ Small-scale production up to 70 mL/min

INCLUDES
✔ 5 KNAUER IJMs
✔ 3 pumps
✔ 2 valves
✔ 3 different API sample loops
IJM NanoScaler commercial
designed for
METHOD DEVELOPMENT AND SCALE-UP
✔ Scale-up with 5 IJMs
✔ Encapsulation at a range of
✔ 500 µL to hundreds of milliliters
✔ Small-scale production up to 70 mL/min

INCLUDES
✔ 5 KNAUER IJMs
✔ 3 pumps
✔ 2 valves
✔ 3 different API sample loops
IJM NanoScaler Pro
designed for
AUTOMATED SCREENING AND SCALE-UP
✔ High-throughput screening with up to 108 samples
✔ Automated premix of different lipid compositions to screen early-stage API candidates
✔ Minimal sample volume of 300 µL
✔ up to 70 mL/min

INCLUDES
✔ 5 KNAUER IJMs
✔ 3 pumps
✔ one Autosampler with cooling option
✔ UV detector
IJM NanoScaler Ultra
designed for
AUTOMATED SCREENING AND SCALE-UP
✔ High-throughput screening with up to 108 samples
✔ Automated premix of different lipid compositions to screen early-stage API candidates
✔ Minimal sample volume of 300 µL
✔ up to 70 mL/min

INCLUDES
✔ 5 KNAUER IJMs
✔ 3 pumps
✔ two Autosampler with cooling option
✔ UV detector
IJM Benchtop NanoProducer
designed for
CLINICAL TRIALS
✔ Compact, GMP-ready design for benchtop use in labs or clinical trials
✔ From concept to clinic: Supports development, scale-up, and GMP batch production
✔ LNP formulation up to 700 mL/min INCLUDES
✔ 3 KNAUER IJMs
✔ 3 pumps
✔ Benchtop module with one flowmeter, PC, switch, valves and mixers
IJM SingleCore NanoProducer
designed for
COMMERCIAL PRODUCTION
✔ API predilution
✔ Online flow and pressure monitoring
✔ Large-scale production up to 1 L/min

INCLUDES
✔ 1 KNAUER IJM
✔ 4 pumps
✔ 4 flowmeters
✔ 1 valve
✔ GMP ready documentation
✔ 21 CFR part 11 and GAMP 5 compliant software
IJM DuoCore NanoProducer
designed for
LARGE-SCALE COMMERCIAL PRODUCTION
✔ Parallel LNP formulation with 2 KNAUER IJMs
✔ Online flow and pressure monitoring
✔ Large-scale production up to 2 L/min

INCLUDES
✔ 2 KNAUER IJMs
✔ 8 pumps
✔ 8 flowmeters
✔ 2 valves
✔ GMP ready documentation
✔ 21 CFR part 11 and GAMP 5 compliant software