LNP Systems

Das Laborsystem für die Formulierung von Lipid-Nanopartikeln
Der IJM NanoScaler beinhaltet fünf verschiedene Impingement Jets Mixer, die es Forschern ermöglicht, optimale Verkapselungsbedingungen zu bestimmen, bevor sie der Prozess auf eine größere IJM NanoProducer-Einheit erweitert wird.

Das Laborsystem für die Formulierung von Lipid-Nanopartikeln
Der IJM NanoScaler beinhaltet fünf verschiedene Impingement Jets Mixer, die es Forschern ermöglicht, optimale Verkapselungsbedingungen zu bestimmen, bevor sie der Prozess auf eine größere IJM NanoProducer-Einheit erweitert wird.

designed for
AUTOMATED SCREENING AND SCALE-UP
✔ High-throughput screening with up to 108 samples
✔ Automated premix of different lipid compositions to screen early-stage API candidates
✔ Minimal sample volume of 300 µL
✔ up to 70 mL/min

INCLUDES
✔ 5 KNAUER IJMs
✔ 3 pumps
✔ one Autosampler with cooling option
✔ UV detector

designed for
AUTOMATED SCREENING AND SCALE-UP
✔ High-throughput screening with up to 108 samples
✔ Automated premix of different lipid compositions to screen early-stage API candidates
✔ Minimal sample volume of 300 µL
✔ up to 70 mL/min

INCLUDES
✔ 5 KNAUER IJMs
✔ 3 pumps
✔ two Autosampler with cooling option
✔ UV detector

designed for
CLINICAL TRIALS
✔ Compact, GMP-ready design for benchtop use in labs or clinical trials
✔ From concept to clinic: Supports development, scale-up, and GMP batch production
✔ LNP formulation up to 700 mL/min INCLUDES
✔ 3 KNAUER IJMs
✔ 3 pumps
✔ Benchtop module with one flowmeter, PC, switch, valves and mixers

System zur Herstellung von Nanopartikeln (LNP, Nanoemulsionen etc.) im Produktionsmaßstab
900 x 915 x 800 mm (BxHxT)

System zur Herstellung von Nanopartikeln (LNP, Nanoemulsionen etc.) im Produktionsmaßstab
1000 x 1290 x 800 mm (BxHxT)

Upgrade Kit for the IJM NanoScaler
✔ Additional sample loop - minimizes sample consumption
✔ Ideal for R&D-scale experiments

INCLUDES
✔ 1 Valve
✔ 1 Set Capillaries IJM NanoScaler Upgrade Kit Lipid Loop

inkl. Eluentenheizer, Kapillaren und Verschraubungen

Upgrade Kit for the IJM NanoScaler
✔ High-throughput screening with up to 108 samples
✔ Automated premix of different lipid compositions to screen early-stage API candidates

INCLUDES
✔ 1 Autosampler with cooling option
✔ 1 UV detector
✔ 1 AZURA® FC 6.1 BIO Fraction Collector
✔ 1 Set Capillaries IJM NanoScaler Pro Upgrade Kit

Upgrade Kit for the IJM NanoScaler Pro
✔ Full automation for high-throughput workflows and complex libraries
✔ Reduces manual handling, increases process efficiency

INCLUDES
✔ 1 Autosampler with cooling option
✔ 1 Set Capillaries IJM NanoScaler Ultra Upgrade Kit

Nur für PurityChrom 6

Upgrade Kit for the IJM NanoScaler
✔ Enables real-time fractionation
✔ Assists with CIP validation

INCLUDES
✔ 1 UV detector
✔ 1 Set Capillaries IJM NanoScaler Upgrade kit UV-Detector

Upgrade Kit for the IJM NanoScaler
✔ Enables real-time fractionation
✔ Assists with CIP validation

INCLUDES
✔ 1 Conductivity monitor
✔ 1 Set Capillaries IJM NanoScaler Upgrade kit Conductivity monitor

Upgrade Kit for the IJM NanoScaler
✔ Fraction collection up to 165 samples per rack
✔ Enables precise inline fractionation
INCLUDES
✔ 1 AZURA® FC 6.1 BIO Fraction Collector
✔ 1 Set Capillaries IJM NanoScaler Upgrade kit Fraction collector

Upgrade Kit for the IJM NanoScaler
✔ Upgrade to stainless steel (SST) capillaries
✔ Improved chemical resistance and cleanability
✔ Ideal for GMP environments and sensitive LNP formulations

INCLUDES
✔ 1 Set Capillaries IJM NanoScaler Upgrade kit SST capillaries

Upgrade Kit for the IJM NanoScaler
✔ Up to 38 mL/min with each pump
✔ Small batch production after process optimization

INCLUDES
✔ 3 High-Flow pump head inlets for the IJM NanoScaler

Accessory for the IJM NanoScaler
✔ Complete capillary replacement kit
✔ All screw fittings included

INCLUDES
✔ 1 Set of capillaries for the IJM NanoScaler (with screw fittings)

Accessory for the IJM NanoScaler
✔ Capillary replacement for the IJM NanoScaler
✔ Reuse existing screw fittings

INCLUDES
✔ 1 Set of capillaries for the IJM NanoScaler (without screw fittings)

Accessory for the IJM NanoScaler
✔ Reduces hold-up volume in the inlet tubing of API/lipid
✔ Enables encapsulation of small batches by direct flow delivery

INCLUDES
✔ 5 Sets of API/lipid supply

Accessory for the IJM NanoScaler
✔ Capillary replacement for the Lipid Loop Upgrade kit
✔ All screw fittings included

INCLUDES
✔ 1 Set of capillaries for the IJM NanoScaler Upgrade kit Lipid Loop (with screw fittings)

Accessory for the IJM NanoScaler
✔ Capillary replacement for the Lipid Loop Upgrade kit
✔ Reuse existing screw fittings

INCLUDES
✔ 1 Set Capillaries IJM NanoScaler Upgrade kit Lipid Loop (without screw fittings)